autoimmune progesterone dermatitis with angioedema caused by exogenous progesterone in a pregnant woman: a case report
نویسندگان
چکیده
conclusions patients with apd may have very different symptoms requiring immediate care; therefore, being informed about this condition is necessary for the physicians in emergency and obstetrics and gynecology departments. also a positive history of such condition in a pregnant woman necessitates precautions in the management of her pregnancy due to the potential of anaphylactic events. introduction autoimmune progesterone dermatitis (apd) is an uncommon immunologic condition accompanied with dermatologic manifestations and caused by an immune response to endogenous or exogenous progesterone in women during their reproductive years. we report a case of apd in a pregnant woman who received exogenous progesterone to prevent preterm delivery. case presentation a 28-year-old female who was 17 weeks pregnant was referred to the emergency department with the complaint of progressive edema in the dorsal side of her right hand and progressive dyspnea. intradermal skin test using 50 mg/ml progesterone resulted in 15 mm wheal in the injected area and approved the diagnosis of apd.
منابع مشابه
Autoimmune Progesterone Dermatitis: A Case Report
Background. Autoimmune progesterone dermatitis is a rare cyclic premenstrual allergic reaction to progesterone produced during the luteal phase of a woman's menstrual cycle. Patients present with a variety of conditions including erythema multiforme, eczema, urticaria, angioedema, and progesterone-induced anaphylaxis. Case. Thirty-eight-year-old woman G2P2002 presents with erythema multiforme a...
متن کاملAutoimmune progesterone dermatitis.
A 35-year-old woman had recurrent urticarial erythemas on her trunk and extremities for 3 years. The eruptions appeared regularly 3 to 5 days prior to menstruation and persisted for several days. The patient showed a positive skin test response to progesterone and had circulating antiprogesterone IgG antibodies. A speculative concept of the possible autoimmune damage to the ovary, the major org...
متن کاملA case of progesterone-induced anaphylaxis, cyclic urticaria/angioedema, and autoimmune dermatitis.
OBJECTIVE Women have exhibited anaphylaxis, urticaria/angioedema, and autoimmune progesterone dermatitis (APD) coinciding with the progesterone premenstrual rise. We report a detailed immunological evaluation of such a woman responsive to a gonadotropin hormone-releasing agonist (GHRA). METHODS Skin testing, enzyme-linked immunosorbent assays (ELISAs), leukocyte histamine release (LHR), and i...
متن کاملAutoimmune Progesterone Dermatitis: Case of a Progressively Worsening Cyclic Rash
Erin Kathleen Fee, MS-III, AZCOM, Candidate for D.O. Degree, [email protected] Dr. Angela DeRosa, DO, MBA, CPE, DeRosa Medical: Scottsdale, AZ, [email protected] Shellee Adams, FNP, DeRosa Medical: Scottsdale, AZ, [email protected] Dr. Charles Finch, DO, FACOEP, Chair, Department of Integrated Medicine, Professor of Emergency Medicine, Arizona College of Osteopathic Medicine: Glen...
متن کاملAutoimmune progesterone dermatitis in a patient with endometriosis: case report and review of the literature
Autoimmune progesterone dermatitis (APD) is a condition in which the menstrual cycle is associated with a number of skin findings such as urticaria, eczema, angioedema, and others. In affected women, it occurs 3-10 days prior to the onset of menstrual flow, and resolves 2 days into menses. Women with irregular menses may not have this clear correlation, and therefore may be missed. We present a...
متن کاملProgesterone Producing Granulosa Cell Tumor: a Case Report
The granulosa cell tumor is the most common malignant functioning tumor of the ovary. When functional, granulosa tumor almost always are estrogenic although rare tumors are androgenic. Progesterone producing by these tumors has only been reported twice. We report a case of granulosa cell tumor in a 7 years old girl with precocious puberty who represent the first case of progesterone producing b...
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عنوان ژورنال:
razavi international journal of medicineجلد ۳، شماره ۳، صفحات ۰-۰
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